Andarine S4 SARM Review: Effects, Dosage, Results

Many bodybuilders and lifters consider anabolic steroids as a means to enhance their performance, build muscle mass, and increase their strength.

These substances have several severe side-effects, however, and you may end up with debilitating health issues if you use them.

With S4, however, you may get the same results without running the health risks.

Since this drug seemingly offers the best of both worlds, it is the obvious consideration for many athletes.

But how safe is S4? Is it the best product to enhance your performance in the gym?

In this Andarine S4 review, we will take a look at what this product is, what it does, and its benefits and side-effects.

This review will also discuss the differences between Andarine and anabolic steroids.

When you reach the end of this article, you will hopefully have enough information to make an informed buying decision.

What Does Andarine Do?

Andarine falls in a category of anabolic-androgenic steroids called Selective Androgen Receptor Modulators (SARMs). The modulators interact with androgen receptors in muscle and bone tissue. The results of this interaction include strength development and body weight loss that are faster than normal.

In essence, the results of using SARMs like Andarine are the same as those of anabolic steroids, but the side-effects are significantly less.

S4 is one of the most effective and popular SARMs on the market, and it has a compound designation of S4. Initially, manufacturers developed this product as a treatment for muscle wasting diseases. It was only a matter of time before bodybuilders and athletes started using it as a safe and legal alternative to anabolic steroids.

This SARM is easy to use and highly effective, thanks to its high bioavailability and long half-life. You only have to take one pill per day to see rapid results.

How Does Andarine Work?

Andarine and some other SARMs have a similar mechanism to anabolic steroids. The androgenic receptors in your body’s cells form a binding to androgens, such as testosterone. When a receptor binds to the androgen, the cell receives a signal to increase protein synthesis and initiate anabolic processes. Andarine modulates this signal in body tissues.

Who Should Take S4?

Andarine is the ideal product for someone who hits their performance limits. However, you should deplete all means available to you before considering S4 SARM. You have to use Andarine in combination with a carefully formulated and rigorous training program and a healthy diet.

If your muscles, strength, and performance are continually improving with training and dieting alone, you may not need S4 yet.

Who Shouldn’t Take S4?

S4 is not a miracle product that will get you in shape with minimal input from your side. If you want to lose a beer belly, you should start on a training program and a healthy meal plan. You only have to consider S4 when extensive training no longer gets you the results you want.

If you are pregnant or breastfeeding, you should also stay away from Andarine. Your hormonal balance plays an integral role in maintaining your pregnancy or milk production, and taking Andarine can potentially be dangerous.

People who suffer from hormonal imbalances or abnormally high testosterone levels should also not take Andarine. We recommend that you consult with your doctor before starting on S4 SARM. After a thorough examination and consideration of your medical history, your doctor will be able to determine your risk of side-effects.

Benefits of Andarine

S-4 has many benefits:

Strength Increase

Taking Andarine will increase your strength significantly. You will be able to lift better, which has long-term benefits in terms of lean mass development. S4 will also enhance your stamina, giving you the ability to train for longer without crashing. Stacking Andarine with Cardarine or LGD will also help to make you stronger.

Cutting Fat

S4 may be a mild SARM, but it is highly effective in increasing the rate of lipolysis, vascularity, and fat loss. These attributes make S4 one of the best SARMs products to add to the last few weeks of your contest prep.

Prevents Muscle Loss

One of the problems with aggressive cuts is that the body tends to catabolize the bulking you worked so hard to develop. Taking S4 SARM will prevent muscle loss while you work to reduce body fat.

Andarine Doesn't Cause Estrogenic or Androgenic Side Effects

Because S4 is a full agonist in muscle and bone tissue, so it promotes the development of bone strength, bone density, and lean mass. However, S4 is a non-hormonal and non-steroidal compound, so you don’t have to worry about androgenic side effects like problems with urine flow, acne, male pattern baldness, or mood changes.

S4 also doesn’t aromatize, and female users will not experience virilization or deepening of the voice.

Low Doses are Sufficient

Another benefit of SARMs S4 is that it is potent, even at a low dose. With as little as 5mg per day, you will be able to notice results in limited time. You will also be able to complete high-intensity exercises while minimizing fatigue.

No Water Retention

Unlike other performance-enhancing drugs, S4 SARMs use is not associated with water retention or bloating. If you are looking to lose water weight, this product is a viable option.

Side-Effects of S4

There are some side-effects as well:

Testosterone Suppression

Like most other common SARMs, prohormones, and anabolic steroids, S-4 suppresses the production of hormones like testosterone. With post cycle therapy (PCT,) you can bring your hormone levels back to normal. You should also keep your cycles short, especially if you take high doses of S4.

Taking long breaks between cycles, controlling your doses, and taking PCT products are crucial with the use of any SARMs – not just S4. Once your testosterone levels are back to normal, you can continue with the next cycle.


Stack Andarine doesn’t only target androgen receptors in the muscle and bone tissues, but also the eyes. As a result, you may experience a yellowish tinge to your vision and a lack of peripheral vision at night. Another vision-related side effect is an adjustment difficulty when moving from a dark area to a light area.

The dosage seems to affect the severity of this side-effect. If you take low doses, chances are you will not experience this side effect. When you stop taking Andarine, problems with your vision will also disappear.

How to Use Andarine

You can use S4 to achieve any training goal, including strength training, bulking, cutting, or recomping. A lot of bodybuilders use Andarine on its own, but you can stack it with other compounds to focus on individual results as well. When using S4 as a stand-alone selective androgen receptor modulator, try to ramp your dosage up to 50mg per day.

Strength Training

If you want to improve your lifting abilities, stack 50mg of S4 with 10mg of LGD-4033 per day.


When burning fat, you run the risk of losing lean muscle mass. Prevent this from happening by pairing 25mg of Andarine with 20mg of Cardarine per day for as long as you are on a caloric deficit.


If you want to gain mass while burning fat, combine 20mg of Andarine with 25mg of Ostarine, and 20mg of Cardarine per day.


For effective bulking, combine 50mg of S4 with 10mg of RAD140 per day.

How to Take Andarine

Andarine is available in a pill- or liquid form. Take your Andarine in the mornings, preferably around 20 minutes before breakfast. Andarine in pill form is the easiest to take and is the form that a lot of users prefer. When taking Andarine in liquid form, measure the amount you want to take and place it underneath your tongue.

Sublingual liquid enters the bloodstream directly, and it will start working immediately. If you are using Andarine for the first time, start with a small dosage of 5mg per day. Ramp up the dosages gradually to prevent adverse side effects.

Other SARM Alternatives

There are a lot of other SARMs for sale, and most of them are similar to S4 in terms of mechanism, potency, and performance-enhancing benefits. These SARMs include Ostarine and Cardarine.

Ostarine is a supplement enobosarm, and its initial indication was to treat muscle wasting and osteoporosis. You can use Ostarine in the same way as S4 to preserve muscle mass and burn fat.


S4 is a safe and legal alternative to anabolic steroids that are still under review by the Food and Drug Administration (FDA.) This compound is a Selective Androgen Receptor Modulator (SARM) and is the ideal solution to bodybuilders and other users who want to derive the benefits of S-4 steroids, but not the adverse side-effects.

Andarine interacts with androgen receptors in muscles and bone tissue to achieve rapid growth of muscles and loss of body fat. As a result, it offers a wide range of benefits, including strength building and muscle loss prevention during cuts. In combination with other SARMs like RAD140, S-4 can also promote the development of lean muscle mass.

Side-effects of Anadrine include the suppression of hormone production and impaired vision. With proper post cycle therapy, you can return your hormone levels to normal. Problems with vision are only prevalent with high doses, and they are only temporary.

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